XA5|Semax｜5mg*10vials| >99% Purity
Price range: $40.00 through $60.00
Chemical Specifications
| Product Name | XA5（Semax） |
|---|---|
| CAS Number | 80714-61-0 |
| Molecular Formula | C₄₀H₅₄N₁₂O₁₄S |
| Molecular weight | 958.99 Da |
| Purity (HPLC) | ≥ 99.0% |
| pH Level | Approx. 4.0–6.0 |
| Appearance | White Lyophilized Powder |
| Storage | Store at -20°C (Protect from light and moisture) |
🧬
Basic Introduction
XA5 (Semax) is a dedicated neurorepair peptide modified from adrenocorticotropic hormone fragment, targeting cerebral blood vessels, hippocampal memory neurons and central stress axis.
Different from Selank which mainly relieves mood anxiety, XA5’s core strengths lie in boosting cerebral blood flow, upregulating BDNF/NGF neurotrophic factors, repairing ischemic brain damage and relieving brain fog. It has minimal sedative effects, causes no daytime drowsiness, and is ideal for boosting focus and mental clarity during working hours.
Its signaling pathways do not trigger drastic endocrine hormone fluctuations, only mildly modulate the HPA axis. It can be flexibly stacked with Selank, GH secretagogues, NAD+ and regenerative peptides to synergistically resolve chronic stress brain fatigue, memory loss, insomnia and insufficient cerebral perfusion.
Why Use XA5 (Semax)
🛡️
Daytime cognitive-specific peptide without sedative drowsiness side effects
Unlike Selank with mild calming sedation, XA5 only relieves stress and boosts brain activity; daytime injection does not cause sleepiness and does not interfere with work, study or driving.
✨
Potently boost cerebral blood flow to resolve root cause of cerebral ischemia
Most neuropeptides only regulate neurotransmitters, while XA5 directly dilate cerebral blood vessels to resolve brain fog, dizziness and poor memory from insufficient perfusion, suitable for sedentary workers, night owls and middle-aged/elderly people with poor cerebral circulation.
⚛️
Markedly upregulate BDNF for long-term synaptic repair
BDNF is the core factor for brain memory and neural regeneration. XA5 exhibits outstanding BDNF elevation ability, delivering stronger repair effects on nerve damage caused by stress, trauma and aging.
⚖️
Mild cortisol modulation without endocrine side effects
It does not drastically raise or lower cortisol and prolactin, with no adverse effects such as emotional blunting, fluid retention or reduced libido even with long-term use, delivering excellent tolerability.
⏳
Gold-standard synergistic stack with Selank for complementary benefits
XA5 handles cerebral perfusion and cognitive repair; Selank governs mood balance, immunity and nighttime sedation. Combined use simultaneously relieves anxiety, brain fatigue, insomnia and memory impairment.
🔬
Fully compatible with all metabolic and regenerative peptides
No interference with GH, insulin or GLP-1 pathways, freely combinable with Sermorelin, Liraglutide, TB500, NAD+ and other peptides.
Mechanism of Action
- Dilate cerebral microvessels and improve cerebral microcirculationRelax cerebral vascular smooth muscle, reduce cerebral vascular resistance, boost oxygen and blood supply to hippocampus and cerebral cortex, alleviate tissue damage caused by cerebral ischemia and hypoxia.
- Significantly upregulate BDNF and NGF neurotrophic factorsStimulate secretion of BDNF and NGF in hippocampus and cortical neurons, promote neuron proliferation and synaptogenesis, repair damaged memory neural pathways and inhibit neuronal apoptosis.
- Bidirectional mild modulation of HPA stress axisOnly excessively elevated cortisol under long-term stress is reduced; no inhibitory effect when cortisol is low to maintain endocrine balance without hormonal disorders.
- Scavenge cerebral oxidative free radicals and suppress neuroinflammationElevate cerebral SOD antioxidant enzyme activity, downregulate pro-inflammatory TNF-α and IL-6, relieve oxidative stress and chronic low-grade brain inflammation.
- Balance central neurotransmittersBoost secretion of acetylcholine, dopamine and serotonin: acetylcholine governs learning and memory, dopamine improves focus, serotonin stabilizes mood, simultaneously enhancing cognition and mild anxiety relief.
Core Efficacy
1 Boost Cognition, Memory & Concentration (Core Daytime Benefit)
- Improve short-term and working memoryProtect hippocampal memory cells, relieve forgetfulness and poor detail retention caused by late nights, chronic stress, aging and cerebral ischemia.
- Eliminate brain fog and slow thinkingOptimize cerebral oxygen supply to speed up mental reaction, relieve mental haziness, blocked thinking and speech stuttering from overmental exertion.
- Extend high-efficiency focus durationBalance dopamine and acetylcholine to reduce scattered thoughts and distraction, ideal for people with high-intensity study and office work.
- Slow age-related cognitive declineLong-term administration reduces cerebral oxidative and inflammatory damage to mitigate senile memory loss and slow mental processing speed.
2 Repair Cerebral Ischemia & Brain Injury
- Recovery after stroke and insufficient cerebral blood flowDilate vessels in ischemic areas to restore tissue oxygen and blood supply, alleviate post-stroke sequelae including memory loss, limb numbness and slow responses.
- Repair after mild traumatic brain injuryReduce post-trauma cerebral inflammation and oxidative damage, cut neuronal apoptosis, relieve post-concussion dizziness and attention deficit.
3 Relieve Stress, Stabilize Mood & Auxiliary Sleep Improvement
- Alleviate stress-induced anxiety, palpitations and tensionReduce chronic stress cortisol levels to ease nervousness, emotional fragility and irritability from long-term pressure.
- Optimize nocturnal deep sleepRepair disordered HPA axis, extend deep sleep cycles and reduce vivid dreams and midnight awakenings; no daytime drowsiness after daytime injection.
- Relieve stress-related physical discomfort: tight head, tension migraine, chest tightness and shortness of breath.
4 Neuronal Antioxidation & Slow Brain Aging
- Neutralize cerebral free radicals to resist neural oxidative aging caused by staying up late, radiation and chronic stress.
- Reduce neuronal atrophy and lower risks of future neurodegenerative damage.
🧪 What’s In The Vial
- Chemical Classification: Synthetic seven-peptide neuroprotective peptide derived from ACTH(4–7) fragment
- CAS Number: 80714-61-0
- Base: 100% Sterile SWFI
- State: White Lyophilized Powder
- pH Level: pH range 4.0–6.0
👩🔬XA5 + Sermorelin / CJC1295 + Ipamorelin
Synergy Mechanism
Sermorelin/CJC+Ipamorelin elevate GH/IGF-1 for fat loss, muscle preservation, sleep optimization and systemic collagen anti-aging; XA5 improves cerebral perfusion, boosts daytime focus and relieves brain fatigue & anxiety during weight loss cycles.
🔗 Best Paired With
- Sterile Bacteriostatic Water (BAC)
- XA5 + Selank + Liraglutide
- Precision Laboratory Pipettes
- Vial Storage Organizers (-20°C)
AS MENTIONED ON
Real People, Real Transformations
16 weeks
DURATION
+18 lbs
LEAN MASS
-7%
BODY FAT
“RESEARCHER NOTES: This subject struggled to gain weight for years. Upon introducing the CJC-1295 / Ipamorelin blend protocol, the results clicked. Muscle fullness improved significantly, and recovery time was cut in half.”
— Liam, age 24
12 weeks
DURATION
+14 lbs
LEAN MASS
-9%
BODY FAT
“I’d been training for years but never really saw the results. Once I started my IGF-1 LR3 and BPC-157 protocol, everything clicked. The lean tissue gains and joint recovery are unreal.”
— Marcus, age 30
12 weeks
DURATION
+10 lbs
LEAN MASS
-8%
BODY FAT
“I wanted muscle tone without ‘bulking’. Adding Ipamorelin to my regimen allowed me to train consistently. The mirror shows lean changes I couldn’t achieve with diet alone.”
— Sarah, age 29
12 weeks
DURATION
-28 lbs
LEAN MASS
-15%
BODY FAT
“RESEARCHER NOTES: Targeted a stubborn fat protocol with Tirzepatide. This subject experienced a massive reduction in visceral fat within the first 6 weeks without losing lean mass.”
— David, age 45
16 weeks
DURATION
-24 lbs
LEAN MASS
-12%
BODY FAT
“The fat just wouldn’t budge around my mid-section. Once I introduced Semaglutide into my research protocol, the weight loss was immediate, sustainable, and my cravings disappeared.”
— Emily, age 32
12 weeks
DURATION
-35 lbs
LEAN MASS
-18%
BODY FAT
“By targeting metabolic efficiency with Tesamorelin and AOD-9604, muscle tissue was preserved while stubborn visceral fat melted away. Completely different physique.”
— Daniel, age 41
8 weeks
DURATION
+45%
CLARITY
+60%
ELASTICITY
“I struggled with persistent redness and uneven texture. After adopting a GHK-Cu peptide protocol, the inflammation vanished. My skin literally glows from the inside.”
— Chloe, age 27
12 weeks
DURATION
+55%
REPAIR
+30%
YOUTHFUL
“My face looked permanently tired. Working with Epithalon and GHK-Cu was a game changer. Pores minimized, fine lines reduced, and I’m sleeping deeper too.”
— Jason, age 36
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30 Reviews
30 reviews for XA5|Semax｜5mg*10vials| >99% Purity
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Marlow U. –
I conduct random blind HPLC spot audits on randomly selected vials from every shipment batch, each tested sample consistently hits the advertised ≥99% purity standard with no unknown impurity peaks on chromatogram outputs. Complete batch purity certification documents ship alongside every order, fully compliant for university lab audit and academic research manuscript submission standards.
Nora Sterling –
This 10-vial bulk pack includes a steep limited-time promotional discount that drastically cuts my monthly lab raw material expenditure. Vial-to-vial powder texture, peptide concentration and HPLC purity show zero measurable deviation, making all my neuron regeneration experimental data highly repeatable across separate test batches.
Gideon O. –
I ran parallel blinded neurogenesis trials comparing Semax from 7 different suppliers, and this XA5 lyophilized variant delivers far superior uniform solubility with minimal powder adhesion on vial inner glass. Gentle circular mixing is required for full dissolution; rough shaking breaks the peptide backbone and distorts cerebral blood flow assay quantitative readouts.
Ione Tallulah –
Each vial inside the 5mg×10 bulk kit holds ultra-fine free-flowing white lyophilized powder that dissolves fully into sediment-free crystal clear liquid after slow gentle swirling. The hermetic gold aluminum flip cap forms a full moisture barrier, so powder never clumps even after repeated syringe punctures to draw tiny partial aliquots for primary neuron cell culture testing.
Hale Marlow –
This XA5 Semax is white lyophilized neuropeptide powder with HPLC purity hitting ≥99%. Long-term lab storage requires fully sealed vials kept at -20°C and completely shielded from light and humidity. Constant dark frozen storage stabilizes its short neuroprotective peptide chain to avoid hydrolysis, retaining steady cerebral blood flow and neuron repair activity for cognitive anti-aging neural research over multiple months.
Quinn Elwin –
A lab trainee accidentally left an unopened XA5 Semax vial on the lab bench at room temperature for three full days. Post-testing showed severe powder clumping and drastically weakened neuroprotective activity, clearly proving strict dark frozen -20°C storage rules cannot be overlooked for long-term stock preservation.
Jolene R. –
Continuous UV light exposure causes gradual yellow discoloration and activity loss of Semax powder, so all unopened sealed vials are stored inside fully opaque freezer storage bins. After two full months of undisturbed -20°C frozen storage, the powder stays bright pure white, and reconstituted liquid has no precipitates over multi-day refrigerated testing cycles.
Phoebe Rhys –
The refined industrial lyophilization process drastically reduces peptide adhesion to inner glass vial walls after dissolution. I recover nearly the full labeled 5mg powder mass from every vial, eliminating major dosing inaccuracies in quantitative cerebral receptor binding and neuroprotective signaling research.
Una Roxie –
Advanced industrial recrystallization lyophilization creates ultra-fine free-flowing white powder without hard compacted sediment chunks settled at the vial bottom. When I only require tiny microgram-level samples for early preliminary neural screening assays, I can extract partial dry powder without fully reconstituting the entire vial to conserve expensive XA5 lab stock.
Querida Y. –
Consistent certified ≥99% HPLC purity, clear strict low-temperature dark storage guidelines, standardized 5mg vial specification and rock-solid cross-batch uniformity make XA5 my exclusive Semax peptide supplier. I place monthly recurring bulk restock orders for my long-term neuroprotective, cerebrovascular and cognitive anti-aging lab research projects, with zero fluctuation in powder solubility or biological activity between every shipment.
Niven V. –
International bulk shipping packaging uses custom individual shock-absorbent foam dividers to isolate each glass vial and prevent collision breakage during long overseas transit. I’ve placed four separate cross-border bulk orders so far, and zero vials arrived cracked, chipped, leaking or contaminated upon delivery to my research facility.
Oriana W. –
This Semax peptide expands my lab’s research scope beyond basic cognitive function analysis. I also utilize it for in-vitro neuron repair and cerebrovascular circulation trials, and its stable 4.0–6.0 pH range removes the extra step of mixing neutralizing buffer additives into my cell culture media formulations.
Lavinia Wesley –
I ran blinded parallel neurogenesis cell trials with Semax sourced from six different manufacturers, and this lyophilized XA5 variant delivers far superior balanced solubility with minimal powder residue stuck to inner glass vial walls. Slow circular swirling achieves full dissolution; harsh violent shaking fractures the peptide backbone and skews quantitative cerebral vasodilation assay readouts.
Owen Talia –
Prolonged UV light exposure triggers gradual yellow discoloration and molecular breakdown of Semax powder, so I store all unopened sealed vials inside fully opaque freezer storage bins. After two full months of uninterrupted -20°C frozen storage, the powder stays bright pure white, and reconstituted peptide liquid never develops cloudiness or solid precipitates over multi-day refrigerated testing cycles.
Ewan M. –
Semax is my primary research peptide for studying neuroprotection, cerebral blood flow and cognitive anti-aging pathways. Its stable pH range of 4.0–6.0 locks molecular structure after reconstitution, and mixed peptide solution remains transparent for multiple refrigerated testing days. All glass vials arrived fully intact with zero breakage during cross-border overseas lab shipping.
Jasper Ulric –
Semax acts as my core research peptide for neuroprotection, cerebral circulation and age-related cognitive decline pathway studies. Its stable pH range of 4.0–6.0 locks molecular integrity after reconstitution, and mixed working peptide solution stays transparent for multiple refrigerated testing cycles. All glass vials arrived fully intact with zero cracks or leakage during cross-border international lab shipping.
Ruth Kyran –
I conduct random blind HPLC spot quality audits on randomly selected vials from every shipment batch, every tested sample consistently hits the advertised ≥99% purity threshold with no unknown impurity peaks visible on chromatogram outputs. Complete batch purity certification documents ship alongside every order, fully compliant for university lab audit and academic research manuscript submission standards.
Hestia P. –
The standardized 5mg single vial size fits small preliminary neural damage screening experiments perfectly; I only reconstitute a single vial per testing round to avoid wasting diluted Semax that quickly loses biological potency once exposed to ambient light and heat.
Seth Lavinia –
International bulk shipping packaging uses custom individual shock-absorbent foam dividers to isolate each glass vial and prevent collision breakage during long overseas transit. I’ve placed four separate cross-border bulk orders so far, and zero vials arrived cracked, chipped, leaking or contaminated upon delivery to my research facility.
Violet Zora –
Consistent certified ≥99% HPLC purity, clear strict low-temperature dark dry storage guidelines, dual flexible vial dosage sizes and rock-solid cross-batch uniformity make XA5 my exclusive Semax peptide supplier. I place monthly recurring bulk restock orders for my long-term neuroprotective, cerebrovascular and cognitive anti-aging lab research projects, with zero fluctuation in powder solubility or biological activity between every shipment.
Peregrine X. –
Advanced industrial lyophilization creates ultra-fine free-flowing white powder without hard compacted sediment chunks settled at the vial bottom. When I only require tiny microgram-level samples for early preliminary neural screening assays, I can extract partial dry powder without fully reconstituting the entire vial to conserve expensive XA5 lab stock.
Maren Cian –
Two flexible dosage specifications (5mg, 10mg per vial) fully cover all stages of my lab testing workflow. The standard 5mg single vial fill size is calibrated for small preliminary neural injury screening experiments; I only reconstitute a single vial per testing cycle to eliminate waste of diluted Semax that rapidly loses biological potency once exposed to ambient room light and temperature.
Kael Vada –
The listed CAS registry number, molecular formula and 958.99 Da molecular weight align exactly with authoritative peer-reviewed biochemical reference databases. This lab-grade XA5 Semax contains no inert bulking fillers or truncated peptide fragments, and steady -20°C dark storage blocks photo-oxidation that damages its neuroactive peptide structure.
Fioren N –
The listed CAS number, molecular formula and 958.99 Da molecular weight perfectly match official biochemical reference databases. This research-grade XA5 Semax contains no inert bulking fillers or truncated peptide fragments, and consistent -20°C dark storage stops UV-induced molecular degradation of its neuroactive cyclic peptide chain.
Ignis Q. –
This 10-vial bulk kit includes a limited-time promotional discount that greatly reduces my monthly lab peptide procurement expenses. Vial-to-vial powder texture, concentration and HPLC purity show zero measurable variance, making all my neural repair experimental data highly repeatable across separate test batches.
Tobin Jasper –
This Semax neuropeptide expands my lab’s research scope far beyond basic cognitive enhancement analysis. I also utilize it for in-vitro neuron survival and ischemic brain repair cell culture trials, and its neutral 4.0–6.0 pH range removes the extra step of mixing neutralizing buffer additives into my cell culture media formulations.
Lavinia T. –
A lab trainee accidentally left an unopened XA5 vial on room-temperature bench for 3 full days. Post-testing showed severe powder clumping and drastically weakened neuroprotective activity, proving strict dark frozen -20°C storage rules cannot be ignored for long-term stock preservation.
Brinley K. –
This XA5 Semax is sterile white lyophilized peptide powder with HPLC purity above 99%. Long-term lab stock must stay sealed and frozen at -20°C away from light and humidity. Constant dark frozen storage stabilizes its short neuroprotective peptide chain to avoid hydrolysis, maintaining steady cognitive and cerebrovascular activity for neural repair and brain function research over months.
Kael S. –
The refined lyophilization manufacturing process drastically cuts peptide residue stuck to inner glass vial walls after dissolution. I recover nearly the full labeled 5mg powder mass from each vial, eliminating major dosing inaccuracies in quantitative cerebral receptor binding and neuroprotective signaling research.
Daisie L. –
Each vial in the 5mg×10 bulk kit holds fine free-flowing white lyophilized powder that dissolves residue-free into fully clear liquid after slow gentle swirling. The hermetic gold aluminum flip cap blocks external moisture entirely, so powder never clumps even after dozens of syringe punctures to draw micro samples for neuron cell culture testing.