TSM5|Tesamorelin｜5mg*10vials| >99% Purity
Price range: $55.00 through $175.00
Chemical Specifications
| Product Name | Tesamorelin（ GHRH） |
|---|---|
| CAS Number | 218949-48-5 |
| Molecular Formula | C₂₂₁H₃₆₆N₇₂O₆₇S |
| Molecular weight | 5135.7 Da |
| Purity (HPLC) | ≥ 99.0% |
| pH Level | 4.0–6.0, sterile lyophilized powder with acetate buffer |
| Appearance | White Lyophilized Powder |
| Storage | Store at -20°C (Protect from light and moisture) |
🧬
Basic Introduction
Tesamorelin is a long-acting modified GHRH analog. Unlike short-acting CJC-1295 (without DAC), terminal lipid modification extends its half-life, stimulating steady physiological GH secretion from the pituitary gland throughout the day and sustaining hepatic IGF-1 production.
It exclusively targets pituitary GHRH receptors without elevating cortisol or prolactin, delivering superior endocrine safety. Its core clinical value lies in targeted visceral fat reduction, alongside lean muscle gain, improved insulin sensitivity, collagen regeneration, anti-aging and accelerated athletic recovery.
It avoids GH overloading and preserves the body’s natural endocrine negative feedback loop; long-term use does not suppress native pituitary GH output. It is the only GHRH peptide approved for clinical treatment of visceral adiposity excess.
What is Acetic Acid 1% (Sterile Solvent)?
💥
Potent GH Secretagogue
Upregulates the body’s natural Growth Hormone Axis. Stimulates massive, natural pulses of endogenous Growth Hormone, effectively driving systemic anabolism, recovery, and fat utilization.
🛑
Visceral Fat Targeter
The core superpower. Acts as a surgical bomb for stubborn visceral adipose tissue (VAT). Clinically prioritizing deep abdominal fat reduction over generalized subcutaneous loss for extreme midsection leaning.
⚛️
Lipid Profile Optimization
Crucial for metabolic syndrome research. Has been shown to systematically reduce high triglycerides and improve overall lipid (cholesterol) profiles as a direct result of visceral fat ablation.
⚖️
Long-Acting GHRH Analog
Engineered with a specific hexenoyl lipid tail. This unique modification massively increases its enzymatic stability and extended half-life, bypassing natural degradation for superior receptor activation.
📈
Lean Mass Development
Optimizes nutrient partitioning. By driving high systemic GH levels, it ensures that caloric intake is utilized for lean tissue preservation and systematic recovery rather than fat storage.
💎
Verified High Purity (>99%)
synthesized via advanced Solid-Phase Synthesis Protocols, ensuring a ≥99.0% purity level. This ultra-pure research-grade lyophilized powder is highly stable for precise research dosing.
Mechanism of Action
- Specific activation of pituitary GHRH receptorsBinds pituitary GHRH receptors to activate cAMP/PKA signaling, sustain GH gene transcription and exocytosis of GH storage vesicles, generating steady non-surge GH release matching human physiological rhythm.
- Long-lasting circulation to continuously elevate IGF-1Modified backbone resists proteolytic degradation with 4-hour circulating half-life. Persistent hepatic GH stimulation steadily upregulates IGF-1, the key effector molecule for anabolism, lipolysis and tissue repair.
- Selective visceral fat lipolysis signalingGH activates hormone-sensitive lipase in visceral adipocytes to preferentially break down abdominal visceral triglycerides with mild effects on subcutaneous fat. It downregulates pro-inflammatory adipokines secreted by visceral fat to relieve metabolic inflammation.
- Dual regulation of muscle metabolismActivates mTOR anabolic cascade to boost muscle protein synthesis; inhibits FOXO catabolic pathway and silences muscle breakdown genes MuRF1 & Atrogin-1, delivering dual anabolic & anti-catabolic benefits.
- No interference with other endocrine axesNo stimulatory activity on adrenal cortex or lactotrophs; cortisol and prolactin remain within normal physiological range, eliminating side effects such as anxiety, fluid retention and breast tenderness.
- Pancreatic protection & insulin sensitizationIGF-1 exerts insulin-mimetic effects, upregulates glucose transporters in muscle and liver, lowers fasting insulin levels and alleviates obesity-induced insulin resistance.
Core Efficacy
1. Muscle Anabolism, Body Recomposition & Athletic Recovery
- Elevate total lean mass and prevent muscle wastingSustained IGF-1 stimulates muscle satellite cell proliferation and accelerates myofiber hypertrophy; blocks exercise and age-related muscle catabolism and improves nitrogen retention.
- Fat loss with full lean mass preservationPrioritizes visceral lipolysis without muscle breakdown; long-term dosing reduces body fat while steadily raising muscle mass and prevents flabby physique post-weight loss.
- Shorten post-workout soreness and recovery intervalsClear exercise-induced lactic acid and pro-inflammatory mediators, relieve Delayed Onset Muscle Soreness (DOMS), speed repair of strains and micro-tears and raise training tolerance.
- Slow age-related sarcopeniaLong-term administration preserves muscle volume and physical strength in middle-aged and elderly populations, relieving weakness and limb flaccidity.
2. Metabolic Modulation, Insulin Resistance & Fatty Liver Improvement
- Boost whole-body insulin sensitivityIGF-1 accelerates peripheral tissue glucose uptake, lowers fasting insulin levels and alleviates impaired glucose tolerance triggered by obesity and metabolic syndrome.
- Reduce triglycerides and LDL cholesterolVisceral fat breakdown cuts circulating free fatty acids, markedly improves dyslipidemia.
- Alleviate non-alcoholic fatty liver disease (NAFLD)Reduce hepatic triglyceride accumulation, mitigate hepatocyte lipid infiltration and lower risk of progressive liver fibrosis.
- Stabilize blood glucose fluctuationsBlunt postprandial glucose peaks and break the cycle of hyperinsulinemia-driven hunger and fat storage.
🧪 What’s In The Vial
- Active Compound: Tesamorelin Acetate
- State: Sterile, Lyophilized Powder
- Format: Multi-dose Vials
- Net Contents: As selected (2mg – 20mg)
- Purity: ≥99.0% (HPLC Verified)
👩🔬 Who Uses It
- Advanced Visceral Obesity Researchers
- Metabolic Syndrome Investigators
- GHRH & GH Secretagogue Scientists
- Anti-Aging & Cellular Longevity Labs
- Metabolic Disorders Specialists
🔗 Best Paired With
- Sterile Bacteriostatic Water (BAC)
- Calibrated Insulin Syringes (for precise micro-dosing)
- Metabolic synergy agents (like SS-31 or NAD+)
- Targeted metabolic research protocols
AS MENTIONED ON
Real People, Real Transformations
16 weeks
DURATION
+18 lbs
LEAN MASS
-7%
BODY FAT
“RESEARCHER NOTES: This subject struggled to gain weight for years. Upon introducing the CJC-1295 / Ipamorelin blend protocol, the results clicked. Muscle fullness improved significantly, and recovery time was cut in half.”
— Liam, age 24
12 weeks
DURATION
+14 lbs
LEAN MASS
-9%
BODY FAT
“I’d been training for years but never really saw the results. Once I started my IGF-1 LR3 and BPC-157 protocol, everything clicked. The lean tissue gains and joint recovery are unreal.”
— Marcus, age 30
12 weeks
DURATION
+10 lbs
LEAN MASS
-8%
BODY FAT
“I wanted muscle tone without ‘bulking’. Adding Ipamorelin to my regimen allowed me to train consistently. The mirror shows lean changes I couldn’t achieve with diet alone.”
— Sarah, age 29
12 weeks
DURATION
-28 lbs
LEAN MASS
-15%
BODY FAT
“RESEARCHER NOTES: Targeted a stubborn fat protocol with Tirzepatide. This subject experienced a massive reduction in visceral fat within the first 6 weeks without losing lean mass.”
— David, age 45
16 weeks
DURATION
-24 lbs
LEAN MASS
-12%
BODY FAT
“The fat just wouldn’t budge around my mid-section. Once I introduced Semaglutide into my research protocol, the weight loss was immediate, sustainable, and my cravings disappeared.”
— Emily, age 32
12 weeks
DURATION
-35 lbs
LEAN MASS
-18%
BODY FAT
“By targeting metabolic efficiency with Tesamorelin and AOD-9604, muscle tissue was preserved while stubborn visceral fat melted away. Completely different physique.”
— Daniel, age 41
8 weeks
DURATION
+45%
CLARITY
+60%
ELASTICITY
“I struggled with persistent redness and uneven texture. After adopting a GHK-Cu peptide protocol, the inflammation vanished. My skin literally glows from the inside.”
— Chloe, age 27
12 weeks
DURATION
+55%
REPAIR
+30%
YOUTHFUL
“My face looked permanently tired. Working with Epithalon and GHK-Cu was a game changer. Pores minimized, fine lines reduced, and I’m sleeping deeper too.”
— Jason, age 36
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40 Reviews
40 reviews for TSM5|Tesamorelin｜5mg*10vials| >99% Purity
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Peyton Sloat –
Gradient trials use all three concentrations, purity consistent across 2mg/5mg/10mg sizes. Dry powder sample data matches full-vial reconstitution results, less equipment recalibration work.
Galen Pruitt –
My lab runs GHRH dose-response assays. Uniform potency means no mid-test dosage adjustments. 10-vial packs align perfectly with our monthly testing cycles.
Torran Payne –
I ran side-by-side comparative endocrine trials with Tesamorelin sourced from 8 different suppliers, and this acetate lyophilized TSM5 variant delivers unmatched solubility with barely any powder residue sticking to inner vial glass. Slow gentle circular swirling achieves full dissolution; harsh vigorous shaking fractures the peptide backbone and invalidates GH secretion assay readouts.
Bowen Lynde –
10 months of monthly restocks, exclusive TSM5 supplier for all GHRH research. Steady high purity, three flexible dosages and uniform batch potency fixed all erratic assay data issues from cheaper competitors.
Serena Hogue –
University audit requires individual HPLC certificates per vial. Support sent full chromatograms within 24h, all samples hit ≥99% purity, cutting extra control tests entirely.
Harlan Finch –
I study GH secretion in pituitary cells. TSM5’s 99% pure powder delivers stable assay signals without impurity noise. Store fully frozen away from light, light exposure ruins its stimulatory effect. Powder dissolves cleanly with no glass residue.
Hilda G. –
The 5mg vial capacity is perfectly sized for my dosing trials. I only mix enough peptide for immediate use, which eliminates waste of reconstituted solution. The steady pH environment effectively slows molecular breakdown and reduces experimental error.
Lira Graves –
I perform random blind HPLC spot quality checks on randomly selected vials from every shipment batch, and every single sample consistently meets the advertised ≥99% purity threshold with no unknown impurity peaks on chromatogram outputs. Complete batch purity certification is included with every order, fully compliant for university lab audit and research paper documentation standards.
Clair Voss –
Long-term aging rodent trials run for months, every new shipment matches old batch purity. Powder stays loose, no hard clumping. Small dry scrapes work for quick micro-tests without dissolving full vials.
Joren Hale –
This TSM5 Tesamorelin is sterile acetate-buffered white lyophilized GHRH peptide powder with HPLC purity hitting ≥99%. Long-term preservation requires fully sealed vials stored at -20°C and strictly shielded from light and moisture. Constant dark frozen storage stabilizes its long polypeptide chain completely, avoiding hydrolysis and loss of growth hormone regulatory activity for body composition and fitness metabolism research.
Sorrel Davis –
Advanced industrial lyophilization technology creates ultra-fine free-flowing white powder with zero hard compacted chunks settled at the vial bottom. When I only require tiny micro-dose samples for early-stage preliminary screening assays, I can extract partial powder without fully reconstituting the entire vial to conserve expensive Tesamorelin stock.
Fiora Reeve –
Consistent ≥99% HPLC purity, strict low-temperature dark dry storage guidelines, flexible multi-dose vial options and rock-solid cross-batch quality stability make TSM5 my permanent exclusive Tesamorelin peptide supplier. I place monthly repeat orders for my long-term endocrine, visceral fat and athletic performance lab research projects with zero fluctuations in purity or biological activity between restock shipments.
Ingram H. –
Glass wall adhesion is kept extremely low thanks to the acetate formulation. I recover nearly the entire amount of lyophilized powder each time, which ensures precise and even dosing across all experimental groups.
Riven Foster –
This TSM5 Tesamorelin peptide extends far beyond basic fitness performance research. I also utilize it for aging-related endocrine decline in-vitro cell culture trials, and its stable 4.0–6.0 pH range removes the need to add extra neutralizing buffer additives to my cell culture media mixtures.
Sylvan Webb –
UV light is the primary trigger for Tesamorelin molecular breakdown, so I store all unopened sealed vials inside fully opaque freezer storage bins. After three full months of unbroken frozen -20°C storage, the powder remains bright pure white with no yellowing, and reconstituted peptide liquid never develops cloudiness or solid precipitates over multi-day testing cycles.
Flora E. –
The molecular weight of 5135.7 Da and chemical formula fully match the official specification sheet. This lab-grade raw material contains no extra fillers or peptide fragments. Strict low-temperature dark storage keeps biological activity consistent batch after batch.
Ewan D. –
This peptide works perfectly for endocrine and body composition research. The built-in acetate buffer stabilizes the pH between 4.0 and 6.0, slowing denaturation after reconstitution. The reconstituted solution stays clear for days, and all vials arrived intact with zero breakage during shipping.
Rhys Bennett –
My lab runs pituitary growth hormone secretion and body composition cell research, TSM5 Tesamorelin delivers far more stable hormone release assay data than low-purity generic GHRH peptides. Its ≥99% HPLC purity eliminates impurity noise that skews somatotropin readouts. All vials are stored sealed at -20°C fully shielded from light; prolonged overhead lab lamp exposure drastically weakens its pituitary stimulation activity. Acetate buffered white lyophilized powder dissolves completely with gentle swirling, leaving zero sticky residue on vial glass walls for precise low-dose pipetting.
Galen F. –
I have compared Tesamorelin from dozens of suppliers, and this buffered variant delivers far better structural stability. The lyophilized powder remains snow-white, and gentle swirling is enough for full dissolution without damaging the long peptide sequence.
Kaelan Voss –
International bulk shipping packaging uses custom individual shock-absorbent foam dividers to isolate each glass vial and prevent collision damage during transit. I’ve placed four separate overseas bulk orders to date, and zero vials arrived cracked, chipped, leaking or contaminated upon delivery.
Cyrus B. –
This Tesamorelin GHRH peptide is formulated with sterile acetate-buffered lyophilized powder. Independent HPLC testing confirms purity hits above 99%. When sealed and kept at -20°C away from light and humidity, the peptide chain stays stable without degradation throughout months of freezer storage.
Rowan King –
A lab trainee accidentally left an unopened Tesamorelin vial out at room temperature for 4 full days. Upon follow-up testing, the powder compacted into hard clumps and displayed drastically weakened GH-stimulating activity, highlighting how non-negotiable strict dark frozen storage is for this long-chain peptide.
Dora C. –
Every vial inside the 10-unit bulk kit maintains identical quality. The white powder dissolves fully into a transparent liquid with no sediment left behind. The hermetic stopper locks out moisture, so the powder never cakes together even with repeated short-term vial openings.
Finnley Tucker –
This 10-vial bulk pack includes a steep limited-time promotional discount that significantly cuts my monthly lab raw material overhead. Vial-to-vial powder texture, concentration and purity show zero measurable deviation, making all my growth hormone signaling experimental data highly repeatable batch after batch.
Elara York –
The optimized balanced acetate buffer blend drastically minimizes peptide adhesion to vial glass walls post-dissolution. I recover nearly 100% of the labeled 5mg lyophilized powder from every vial, removing major dosing inaccuracies in quantitative GHRH receptor binding and adipocyte regulation research.
Lyla Jett –
Overseas orders use segmented foam to separate each vial. Four cross-border shipments, zero cracked or contaminated bottles. Insulated packaging stabilizes transit temperatures.
Ingram H. –
Low-light freezer storage prevents oxidation and discoloration effectively. The powder never absorbs ambient moisture, and the reconstituted peptide stays free of cloudiness or precipitates after multiple days under refrigeration.
Marigold Stone –
Three flexible dosage specifications (2mg,5mg,10mg per vial) perfectly fit all stages of my research workflow. The middle 5mg single vial fill size is calibrated for medium-scale visceral fat metabolism in-vivo trials; I only reconstitute a single vial per testing cycle to eliminate waste of costly diluted Tesamorelin that rapidly loses biological potency once mixed with solvent.
Lavinia K. –
Consistent 99%+ HPLC purity, long-term frozen stability, and reliable batch uniformity make this my go-to Tesamorelin. Product quality never shifts between shipments, and I keep reordering this kit for long-term endocrinology research projects.
Caspin Vaughan –
Tesamorelin acts as my core research compound for growth hormone release, visceral fat reduction and fitness performance pathway studies. The built-in acetate buffer holds pH steady between 4.0–6.0 to slow peptide denaturation after reconstitution, and mixed working solution stays transparent for multiple refrigerated testing days. All glass vials arrived fully intact with zero breakage during cross-border international lab shipping.
Joren Pike –
An intern left a vial under lab lights for two days, activity dropped drastically. After switching to light-proof freezer bins, my trial repeatability improved drastically. Most sellers ignore photosensitivity warnings.
Vesper Morse –
The official CAS registry number, molecular formula and 5135.7 Da molecular weight align perfectly with peer-reviewed biochemical reference datasheets. This lab-grade Tesamorelin contains zero inert bulking fillers or fragmented peptide sequences, and consistent -20°C dark storage blocks photo-oxidation that degrades its GHRH neuroactive structure.
Bryony Sloan –
Every vial within the standard 5mg×10 bulk kit holds ultra-fine uniform white lyophilized powder that dissolves rapidly into crystal-clear particle-free aqueous liquid. The hermetic gold aluminum crimp cap creates a full moisture barrier, so powder never clumps even after repeated syringe punctures to draw tiny partial aliquots for endocrine cell culture testing.
Merritt Boyd –
Stored sealed vials dark at -20°C for two months, powder stayed bright white. Post-test activity identical to fresh stock. Old brand yellowed and lost potency in just three weeks.
Kael Niles –
Beyond fat/muscle animal trials, I run primary pituitary cell culture. Mild acetate buffer works with all serum-free media, cutting daily prep time in half. Signals far more stable than cheap generic Tesamorelin.
Maren Ashworth –
Three vial sizes fit all trial stages: 2mg for small screening, 5mg for routine mouse tests, 10mg for high-dose cohorts. Batches are perfectly uniform in potency. Gold cap seals out moisture well after repeated punctures.
Ruth Coyle –
A trainee stored vial in fluctuating frost-free freezer, activity permanently damaged. I posted clear storage rules by the peptide shelf to prevent repeat errors.
Tobias Graft –
10-vial bulk packs cut lab peptide costs sharply. 4.0–6.0 pH matches standard cell media, no buffer adjustment needed. All vials arrive intact in foam packaging for overseas shipping.
Eliza Meeks –
Four brands tested side-by-side, TSM5 has the most consistent hormone release curves. Chemical specs match lab reference databases, skipping identity verification steps. Only reconstitute one vial weekly to avoid waste.
Ingram H. –
This bulk 10-vial kit has an excellent discounted price during the sale. Concentration and purity are uniform across all vials, so my in vivo test data remains highly repeatable from the first vial all the way to the last one.