TB5(BT)|TB500(Thymosin B4 Acetate)｜5mg*10vials | >99% Purity
Price range: $65.00 through $190.00
Chemical Specifications
| Product Name | TB5(BT)(TB500 (Thymosin Beta 4 Acetate)) |
|---|---|
| CAS Number | 77591-33-4 |
| Molecular Formula | C₂₁₂H₃₅₀N₅₆O₇₈S |
| Molecular weight | 4963.4 Da |
| Purity (HPLC) | ≥ 99.0% |
| pH Level | 4.0–6.0, sterile lyophilized powder with acetate buffer |
| Appearance | White Lyophilized Powder |
| Storage | Store at -20°C (Protect from light and moisture) |
🧬
Basic Introduction
TB500 is full-length bioactive thymosin beta 4 naturally present in human tissues and cells. Its core function is regulating actin cytoskeleton, driving directional cell migration and stimulating microvascular angiogenesis, acting as a master signaling molecule for tissue regeneration.
After tissue injury, TB500 guides fibroblasts, keratinocytes and endothelial cells to rapidly migrate toward wounds, tears and inflamed damaged areas. Meanwhile it upregulates growth factors VEGF and FGF to rebuild local blood perfusion, accelerating repair of epithelium, muscle, tendon, bone, skin and mucosa.
It complements BPC-157 via distinct repair pathways: BPC-157 focuses on anti-fibrosis, mucosal protection and chronic inflammation balance; TB500 specializes in cell migration and angiogenesis. Combined use multiplies healing speed, and TB500 is a core regenerative ingredient of the GLOW70 triple-peptide blend.
It has no hormonal activity and does not interfere with GH, cortisol, insulin or other endocrine axes, enabling flexible synergistic stacking with GH secretagogues, GLP‑1 weight-loss peptides, neuropeptides and NAD+ coenzyme.
What is TB500 (Thymosin Beta 4 Acetate)?
🛡️
Unique dual pathways of cell migration + angiogenesis, far faster healing than standard repair peptides
Most repair peptides only stimulate cell proliferation; TB500 simultaneously drives cell mobilization and vascular reconstruction, delivering outstanding efficacy for ischemic lesions, chronic old injuries and large-area wounds.
✨
Zero hormonal interference, fully compatible with all peptides and coenzymes
It does not alter secretion of GH, insulin, cortisol or sex hormones, allowing flexible stacking with weight-loss peptides, GH secretagogues, neuropeptides and NAD+ without endocrine conflict risks.
⚛️
Exceptional efficacy for chronic, long-standing injuries
For years-old tendon strain, mature scars, persistent leaky gut and poor scalp microcirculation, it steadily improves local blood flow and gradually remodels fibrotic tissue.
⚖️
Full-system versatility, repairs muscle, bone, skin, intestine and scalp tissues
One single peptide addresses multiple demands including sports injuries, aesthetic recovery, skin anti-aging, sensitive gut and hair thinning, acting as a multi-functional regenerative agent.
⏳
Low immunogenicity with excellent injection tolerance
It is an endogenous human peptide fragment, rarely causing persistent injection site redness or allergic reactions, suitable for repeated long-term administration.
🔬
Gold-standard synergy with BPC‑157 to offset each other’s limitations
TB500 opens blood perfusion and cell migration pathways; BPC‑157 blocks scar fibrosis and protects mucosa. Combined use triples to quintuple tissue repair speed.
Mechanism of Action
- Regulate actin cytoskeleton to accelerate directional cell migrationTB500 sequesters actin monomers and remodels cellular cytoskeleton, drastically boosting crawling speed of keratinocytes, fibroblasts and endothelial cells to rapidly cover wounds and fill tissue defects.
- Upregulate VEGF & FGF to potently trigger angiogenesisActivate proliferation of endothelial cells at lesion sites to generate brand-new microvessels, delivering oxygen and nutrients to damaged tissue while clearing metabolic waste and inflammatory mediators, resolving ischemia-induced delayed healing.
- Inhibit excessive cellular apoptosis and protect injured cellsUpregulate anti-apoptotic Bcl‑2 protein to reduce cell necrosis caused by oxidative stress, trauma and ischemia, preserve viable tissue and prevent lesion expansion.
- Balance inflammatory response and reduce edema/erythema during healingMildly suppress pro-inflammatory TNF‑α and IL‑1 to limit overactive acute inflammation, shorten swelling and redness cycles and establish a stable microenvironment for regeneration.
- Activate stem cells to drive tissue remodelingStimulate differentiation of local mesenchymal stem cells to accelerate regeneration of dermis, tendon, cartilage and bone, lowering risks of scarring and tissue adhesion.
Core Efficacy
1 Rapid Repair of Sports Soft Tissue Injuries (Primary Application)
- Muscle strains, contusions and Delayed Onset Muscle Soreness (DOMS)Accelerate myofiber migration and local blood perfusion, rapidly clear accumulated lactic acid and inflammation, drastically shorten recovery intervals after strength and high-intensity training and relieve persistent post-workout soreness and fatigue.
- Tendinitis, minor ligament tears and articular wearBoost tendon fibroblast proliferation and collagen synthesis, relieve tennis elbow, rotator cuff injuries and ankle ligament strain, reduce recurrent dull pain of old sports injuries triggered by weather changes.
- Auxiliary healing of bone contusions and minor fissuresActivate osteoblast activity and periosteal angiogenesis to speed callus formation and shorten bone recovery rest periods.
2 Cutaneous Wound Healing & Post-Aesthetic Recovery
- Abrasions, cuts and minor burnsAccelerate keratinocyte migration to close wounds, boost granulation tissue growth, shorten healing duration and reduce risks of post-healing hyperpigmentation and hypertrophic scars.
- Recovery after laser, fractional, microneedling and mesotherapy proceduresQuickly fade post-treatment erythema and edema, speed epidermal barrier reconstruction, shorten scabbing time and lower risks of worsened pigmentation and acne marks.
- Fade old hypertrophic scars and soften hard scar tissueSustain dermal cell regeneration and rearrange collagen fibers to soften raised scars and lighten scar discoloration.
3 Skin Anti-Aging, Barrier Repair & Scalp Care
- Dermal collagen regeneration, firming and wrinkle reductionImprove dermal blood perfusion and stimulate continuous collagen & elastin synthesis by fibroblasts, relieving photoaging fine lines and rough facial sagging.
- Repair damaged sensitive skin barrierAlleviate seasonal redness, telangiectasia and irritant dermatitis, strengthen skin tolerance.
- Improve scalp microcirculation & auxiliary anti-hair lossDilate scalp microvessels to deliver nutrients to hair follicles, prolong hair anagen growth phase and relieve dry itchy scalp and thin shedding hair.
4 Mucosal Barrier Repair (Intestinal & Respiratory)
- Relieve leaky gut and irritable bowel syndromeAccelerate intestinal epithelial cell migration to repair damaged intestinal wall, strengthen tight junctions, mitigate chronic intestinal low-grade inflammation and relieve bloating and food intolerance.
- Respiratory mucosal repairSoothe allergic airway inflammation, repair damaged airway epithelium and relieve dry cough and sensitive throat.
5 Systemic Neuroprotection & Chronic Inflammation Relief
🧪 What’s In The Vial
- White Lyophilized Powder: TB500 (Thymosin Beta 4 Acetate)
- CAS Number: 77591-33-4
- Base: 100% Sterile SWFI
- State: White Lyophilized Powder
- pH Level: 4.0–6.0, sterile lyophilized powder with acetate buffer
👩🔬 TB500 + GHK‑Cu + NJ100 (NAD+)
- Synergy Mechanism
TB500 opens dermal microvessels and speeds cell regeneration; GHK‑Cu boosts collagen synthesis, antioxidation and fades red acne marks; NJ100 enhances cellular DNA repair and systemic antioxidation to slow photoaging. Combined internal & external synergy firms and brightens skin and shortens post-laser/microneedling recovery time.
🔗 Storage Conditions
Unreconstituted lyophilized powder: Long-term sealed storage at -20°C away from light;
Reconstituted solution: Refrigerate at 2–8°C protected from light and finish within 14 days, avoid repeated freeze-thaw cycles and violent shaking.
AS MENTIONED ON
Real People, Real Transformations
16 weeks
DURATION
+18 lbs
LEAN MASS
-7%
BODY FAT
“RESEARCHER NOTES: This subject struggled to gain weight for years. Upon introducing the CJC-1295 / Ipamorelin blend protocol, the results clicked. Muscle fullness improved significantly, and recovery time was cut in half.”
— Liam, age 24
12 weeks
DURATION
+14 lbs
LEAN MASS
-9%
BODY FAT
“I’d been training for years but never really saw the results. Once I started my IGF-1 LR3 and BPC-157 protocol, everything clicked. The lean tissue gains and joint recovery are unreal.”
— Marcus, age 30
12 weeks
DURATION
+10 lbs
LEAN MASS
-8%
BODY FAT
“I wanted muscle tone without ‘bulking’. Adding Ipamorelin to my regimen allowed me to train consistently. The mirror shows lean changes I couldn’t achieve with diet alone.”
— Sarah, age 29
12 weeks
DURATION
-28 lbs
LEAN MASS
-15%
BODY FAT
“RESEARCHER NOTES: Targeted a stubborn fat protocol with Tirzepatide. This subject experienced a massive reduction in visceral fat within the first 6 weeks without losing lean mass.”
— David, age 45
16 weeks
DURATION
-24 lbs
LEAN MASS
-12%
BODY FAT
“The fat just wouldn’t budge around my mid-section. Once I introduced Semaglutide into my research protocol, the weight loss was immediate, sustainable, and my cravings disappeared.”
— Emily, age 32
12 weeks
DURATION
-35 lbs
LEAN MASS
-18%
BODY FAT
“By targeting metabolic efficiency with Tesamorelin and AOD-9604, muscle tissue was preserved while stubborn visceral fat melted away. Completely different physique.”
— Daniel, age 41
8 weeks
DURATION
+45%
CLARITY
+60%
ELASTICITY
“I struggled with persistent redness and uneven texture. After adopting a GHK-Cu peptide protocol, the inflammation vanished. My skin literally glows from the inside.”
— Chloe, age 27
12 weeks
DURATION
+55%
REPAIR
+30%
YOUTHFUL
“My face looked permanently tired. Working with Epithalon and GHK-Cu was a game changer. Pores minimized, fine lines reduced, and I’m sleeping deeper too.”
— Jason, age 36
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30 Reviews
30 reviews for TB5(BT)|TB500(Thymosin B4 Acetate)｜5mg*10vials | >99% Purity
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Juno Page –
Three flexible dosage specifications (2mg, 5mg, 10mg per vial) perfectly fit all stages of my research workflow. The standard 5mg single vial size matches medium-scale in-vivo soft tissue recovery trials perfectly; I only reconstitute a single vial per testing session to avoid wasting diluted TB500 that rapidly loses biological potency once exposed to ambient light and room temperature.
Lavinia Vale –
International bulk shipping packaging uses custom individual shock-absorbent foam dividers to isolate each glass vial and prevent collision breakage during long overseas transit. I’ve placed four separate cross-border bulk orders so far, and zero vials arrived cracked, chipped, leaking or contaminated upon delivery to my research facility.
Vada Voss –
Consistent certified ≥99% HPLC purity, clear strict low-temperature dark dry storage guidelines, three flexible vial dosage sizes and rock-solid cross-batch uniformity make TB5(BT) my exclusive TB500 Thymosin Beta 4 acetate peptide supplier. I place monthly recurring bulk restock orders for my long-term athletic recovery, wound healing and vascular regeneration lab research projects, with zero fluctuation in powder solubility or biological activity between every shipment.
Cian Rowe –
I conduct random blind HPLC spot quality audits on randomly selected vials from every shipment batch, every tested sample consistently hits the advertised ≥99% purity threshold with no unknown impurity peaks visible on chromatogram outputs. Complete batch purity certification documents ship alongside every order, fully compliant for university lab audit and academic research manuscript submission standards.
Talia Morris –
This TB500 peptide expands my lab’s research scope far beyond basic athletic soft tissue recovery analysis. I also utilize it for microvascular regeneration and inflammatory skin repair in-vitro cell culture trials, and its stable 4.0–6.0 pH range removes the extra step of mixing neutralizing buffer additives into my cell culture media formulations.
Ulric Foster –
Advanced industrial lyophilization manufacturing creates ultra-fine free-flowing white powder without hard compacted sediment chunks settled at the vial bottom. When I only require tiny microgram-level samples for early preliminary screening assays, I can extract partial dry powder without fully reconstituting the entire vial to conserve expensive TB500 lab stock.
Marlow Vale –
I ran blinded parallel wound healing cell trials with TB500 from six different suppliers, and this acetate co-lyophilized TB5(BT) variant delivers far more balanced solubility with minimal powder residue stuck to inner glass vial walls. Slow circular swirling achieves full dissolution; harsh violent shaking fractures the peptide backbone and skews quantitative angiogenesis assay readouts.
Lavinia Sloane –
The listed CAS registry number, molecular formula and 4963.4 Da molecular weight align exactly with authoritative peer-reviewed biochemical reference databases. This lab-grade TB5(BT) contains no inert bulking fillers or fragmented peptide fragments, and constant -20°C dark storage blocks photo-oxidation that damages its tissue regenerative amino acid structure.
Zoraida Rainer –
Each vial inside the 5mg×10 bulk kit holds uniform fine white lyophilized powder that dissolves fully into sediment-free clear liquid after slow gentle swirling. The hermetic gold aluminum flip cap forms a complete moisture barrier, so powder never clumps even after repeated syringe punctures to draw tiny partial aliquots for wound repair epithelial cell culture testing.
Marlow Keane –
This TB5(BT) TB500 is sterile acetate-buffered white lyophilized peptide powder with HPLC purity ≥99%. Long-term lab stock must be fully sealed and stored at -20°C away from light and moisture. Constant dark frozen storage stabilizes its long amino acid chain to prevent hydrolysis, maintaining consistent soft tissue repair and angiogenesis activity for athletic recovery & wound healing research for months.
Ulric Voss –
TB500 serves as my core research peptide for soft tissue injury regeneration, microvascular growth and post-exercise recovery pathway studies. The built-in acetate buffer locks pH steadily between 4.0–6.0 to slow peptide denaturation post-reconstitution, and mixed working peptide solution stays transparent for multiple refrigerated testing cycles. All glass vials arrived fully intact with zero breakage during cross-border international lab shipping.
Roxie Frost –
This 10-vial bulk kit comes with a steep limited-time promotional discount that drastically cuts my monthly lab raw material expenditure. Vial-to-vial powder texture, component concentration and HPLC purity show zero measurable deviation, making all my vascular regeneration experimental data highly repeatable across separate test batches.
Rhys Powell –
A lab trainee accidentally left an unopened TB5(BT) vial on the lab bench at room temperature for three full days. Post-testing showed severe powder clumping and drastically weakened tissue regenerative activity, clearly proving strict dark frozen -20°C storage rules cannot be overlooked for long-term stock preservation.
Wesley Frost –
I ran blinded parallel wound healing cell trials with TB500 sourced from six different manufacturers, and this acetate co-lyophilized TB5(BT) variant delivers unmatched solubility with barely any powder residue sticking to inner glass vial walls. Slow circular swirling achieves full dissolution; harsh vigorous shaking fractures the peptide backbone and invalidates quantitative angiogenesis assay readouts.
Elwin Montgomery –
A lab trainee accidentally left an unopened TB5(BT) TB500 vial on the lab bench at room temperature for three full days. Post-testing showed severe powder clumping and drastically weakened tissue regenerative activity, clearly proving strict dark frozen -20°C storage rules cannot be overlooked for long-term stock preservation.
Elowen Knight –
The optimized balanced acetate buffer blend drastically reduces peptide adhesion to inner glass vial walls after dissolution. I recover nearly the full labeled 5mg powder mass from every vial, eliminating major dosing inaccuracies in quantitative angiogenesis and inflammatory tissue signaling research.
Talia Lawrence –
Prolonged UV light exposure triggers gradual yellow discoloration and molecular breakdown of TB500 powder, so I store all unopened sealed vials inside fully opaque freezer storage bins. After two full months of uninterrupted -20°C frozen storage, the powder remains bright pure white, and reconstituted peptide liquid never develops cloudiness or solid precipitates over multi-day refrigerated testing cycles.
Tallulah Bates –
Every vial inside the standard 5mg×10 bulk kit holds ultra-fine free-flowing white lyophilized powder that dissolves fully into sediment-free crystal clear liquid after slow gentle swirling. The airtight gold aluminum flip cap creates a complete humidity barrier, so powder never clumps even after repeated syringe punctures to draw tiny partial aliquots for fibroblast cell culture testing.
Cian Harlow –
This TB5(BT) TB500 is sterile acetate buffered white lyophilized peptide powder with HPLC purity hitting ≥99%. Long-term storage demands sealed vials kept at -20°C with full shielding from light and humidity. Consistent dark frozen storage stabilizes its long peptide chain, avoiding hydrolysis and loss of soft tissue repair activity for athletic recovery and angiogenesis research over multiple months.
Torin Davis –
Prolonged UV light exposure triggers gradual yellow discoloration and molecular breakdown of TB500 powder, so I store all unopened sealed vials inside fully opaque freezer storage bins. After two full months of uninterrupted -20°C frozen storage, the powder stays bright pure white, and reconstituted peptide liquid never develops cloudiness or solid precipitates over multi-day refrigerated testing cycles.
Kyran Bennett –
I conduct random blind HPLC spot quality audits on randomly selected vials from every shipment batch, every tested sample consistently hits the advertised ≥99% purity threshold with no unknown impurity peaks visible on chromatogram outputs. Complete batch purity certification documents ship alongside every order, fully compliant for university lab audit and academic research manuscript submission standards.
Zoraida Rowe –
Consistent certified ≥99% HPLC purity, clear strict low-temperature dark dry storage guidelines, three flexible vial dosage sizes and rock-solid cross-batch uniformity make TB5(BT) my exclusive TB500 Thymosin Beta 4 acetate peptide supplier. I place monthly recurring bulk restock orders for my long-term athletic recovery, wound healing and vascular regeneration lab research projects, with zero fluctuation in powder solubility or biological activity between every shipment.
Jasper Powell –
This TB500 peptide expands my lab’s research scope far beyond basic athletic soft tissue recovery analysis. I also utilize it for in-vitro endothelial differentiation and skin wound repair cell culture trials, and its stable 4.0–6.0 pH range removes the extra step of mixing neutralizing buffer additives into my cell culture media formulations.
Roxie Knight –
Advanced industrial recrystallization lyophilization creates ultra-fine free-flowing white powder without hard compacted sediment chunks settled at the vial bottom. When I only require tiny microgram-level samples for early preliminary injury screening assays, I can extract partial dry powder without fully reconstituting the entire vial to conserve expensive TB5(BT) lab stock.
Vada Wade –
The listed CAS registry number, molecular formula and 4963.4 Da molecular weight align perfectly with peer-reviewed biochemical reference datasheets. This lab-grade TB5(BT) contains no inert bulking fillers or fragmented peptide fragments, and consistent -20°C dark storage blocks photo-oxidation that degrades its tissue-repair active peptide structure.
Sterling Morris –
This 10-vial bulk pack includes a steep limited-time promotional discount that drastically cuts my monthly lab raw material procurement overhead. Vial-to-vial powder texture, peptide concentration and HPLC purity show zero measurable deviation, making all my vascular regeneration experimental data highly repeatable across separate test batches.
Cian Quin –
Three flexible dosage specifications (2mg, 5mg, 10mg per vial) fully cover all stages of my research workflow. The standard 5mg single vial fill size is calibrated for medium-scale in-vivo soft tissue recovery trials; I only reconstitute one vial per testing cycle to eliminate waste of costly diluted TB500 that rapidly loses biological potency once exposed to ambient light and room temperature.
Sterling Quin –
International bulk shipping packaging uses custom individual shock-absorbent foam dividers to isolate each glass vial and prevent collision breakage during long overseas transit. I’ve placed four separate cross-border bulk orders so far, and zero vials arrived cracked, chipped, leaking or contaminated upon delivery to my research facility.
Rhys Ross –
The optimized balanced acetate buffer blend drastically minimizes peptide adhesion to inner glass vial walls after dissolution. I recover nearly 100% of the labeled 5mg lyophilized powder mass from every vial, removing major dosing inaccuracies in quantitative endothelial cell binding and inflammatory tissue signaling research.
Kyran Tovey –
TB500 serves as my core lab compound for soft tissue injury recovery, microvascular regeneration and fitness performance pathway studies. The integrated acetate buffer locks pH within 4.0–6.0 to slow peptide denaturation post-reconstitution, and mixed working liquid stays transparent for multiple refrigerated testing cycles. All glass vials arrived fully intact with zero breakage during cross-border international lab shipping.