IPA5(IP) |Ipamorelin | 5mg*10vials | >99% Purity
Price range: $30.00 through $115.00
Chemical Specifications
| Product Name | Ipamorelin（IPA) |
|---|---|
| CAS Number | 170713-75-4 |
| Molecular Formula | C₃₈H₄₉N₉O₅ |
| Purity (HPLC) | ≥ 99.0% |
| Molecular weight | 711.86 |
| pH Level | 4.0–6.0, sterile lyophilized powder with acetate buffer |
| Appearance | White Lyophilized Powder |
| Storage | Store at -20°C (Protect from light and moisture) |
🧬
Basic Introduction
Ipamorelin is the most selective ghrelin receptor agonist available. Unlike GHRP-2 and GHRP-6, it only activates pituitary GHS-R1a receptors without stimulating adrenal cortex or prolactin-secreting cells, resulting in no elevation of cortisol or prolactin.
Its dual working mechanism: 1) Directly trigger pituitary GH release; 2) Suppress pituitary somatostatin (GH inhibitory hormone) to remove endogenous GH secretion inhibition. It creates dual-pathway synergy with CJC-1295 (Mod GRF 1-29) to boost GH and downstream IGF-1 levels.
It mimics natural nocturnal pulsatile GH secretion, mildly elevates endogenous GH without disrupting hypothalamic-pituitary endocrine negative feedback loops, delivering exceptional tolerability. Core benefits include body recomposition, athletic recovery, deep restorative sleep and systemic anti-aging. It is widely adopted in preclinical animal research covering endocrinology, exercise metabolism and aging.
What is Acetic Acid 1% (Sterile Solvent)?
🛡️
Zero Cortisol/Prolactin Spike
The defining feature of Ipamorelin. Unlike older peptides, it has zero impact on ACTH levels, meaning it will never elevate Cortisol (the muscle-wasting stress hormone) or Prolactin, ensuring a 100% clean GH pulse.
✨
Deep Restorative Sleep
Acts as a profound sleep architect. By mimicking natural nocturnal GH rhythms, it significantly extends the duration of Slow-Wave Sleep (Deep Sleep), which is the critical window for total-body cellular repair.
⚛️
Ultimate Anti-Aging
Provides the perfect hormonal environment for systemic rejuvenation. Research indicates consistent use improves skin elasticity, increases bone mineral density, and reverses the chronological decline of the GH/IGF-1 axis.
🚫
No Extreme Hunger
Unlike its predecessor GHRP-6, Ipamorelin does not violently activate the Ghrelin receptors in a way that triggers extreme gastric motility or uncontrollable carbohydrate cravings. It is a pure, clean secretagogue.
⏳
Clean Lean Mass Retention
By elevating baseline IGF-1 levels without the bloating or water retention associated with exogenous HGH, it creates an ideal metabolic state for preserving and slowly building high-quality, dense muscle tissue.
💎
Verified High Purity (>99%)
Synthesized utilizing precise Solid-Phase Peptide Synthesis (SPPS) and verified by HPLC to ensure ≥99.0% purity. This specific pentapeptide sequence guarantees exact, reproducible research outcomes.
Mechanism of Action
- Highly selective GHS-R1a receptor bindingIpamorelin exclusively targets pituitary GHS-R1a receptors with negligible affinity for adrenal, mammary and other hypothalamic receptors, eliminating common side effects of other potent secretagogues such as anxiety, galactorrhea and fluid retention.
- Dual regulation of GH secretion
- Positive stimulation: Activate calcium signaling to prompt rapid GH exocytosis from pituitary storage vesicles and generate short-term secretion peaks;
- Inhibitory regulation: Downregulate somatostatin synthesis and secretion, reduce endogenous GH inhibitory signals and amplify GH-releasing effects of the GHRH pathway (CJC).
- Mild upregulation of hepatic IGF-1 productionCirculating GH acts on liver to stimulate IGF-1 synthesis, the key effector molecule responsible for muscle anabolism, lipolysis and tissue repair. Ipamorelin avoids sustained GH overload and keeps IGF-1 within steady physiological range.
- No interference with other endocrine axesIt has no activity to boost cortisol, prolactin or aldosterone, so it does not trigger hyperarousal, paradoxical insomnia, breast tenderness or ravenous hunger.
Body Recomposition
1.Lean Muscle Gain & Fat Loss
- Boost muscle protein synthesis and reduce muscle catabolismIGF-1 activates mTOR anabolic pathway to raise muscle nitrogen retention and accelerate myofiber hypertrophy; meanwhile it suppresses FOXO catabolic pathways to cut post-training muscle wasting and increase lean mass.
- Trigger lipolysis with preferential visceral fat breakdownGH activates hormone-sensitive lipase in adipocytes to accelerate triglyceride breakdown for energy; it selectively reduces abdominal visceral fat, shrinks waist circumference and improves central obesity and metabolic syndrome.
- Improve insulin sensitivityIGF-1 delivers insulin-like activity to enhance glucose uptake in muscle and liver tissue, lower fasting insulin levels and alleviate insulin resistance caused by obesity and aging.
- Calorie partitioning effectIngested nutrients are preferentially directed toward muscle anabolism rather than fat storage, enabling fat loss without lean muscle loss without extreme calorie restriction.
2.Athletic Recovery & Musculoskeletal Repair
- Relieve Delayed Onset Muscle Soreness (DOMS)Accelerate regeneration of damaged myocytes, clear lactic acid and pro-inflammatory mediators generated by exercise, drastically shorten recovery intervals after strength and endurance training and raise training frequency tolerance.
- Tendon, ligament and cartilage maintenanceIGF-1 stimulates fibroblast and chondrocyte proliferation to boost collagen and proteoglycan synthesis, relieve tendinitis, minor ligament strain and articular cartilage wear, reduce recurrent pain from old sports injuries.
- Enhance bone metabolismActivate osteoblasts to promote calcium mineral deposition, assist recovery from bone fissures and contusions, slow age-related bone mineral density loss and sarcopenia.
3.Deep Restorative Sleep & Systemic Anti-Aging
- Extend nocturnal deep slow-wave sleepApproximately 70% of human endogenous GH is secreted during deep sleep. Pre-bed Ipamorelin injection mimics natural nighttime GH pulses to prolong deep sleep cycles, reduce frequent waking and vivid dreams, and drastically relieve morning fatigue.
- Slow age-related hormonal declinePituitary GH secretion declines year by year with aging. Ipamorelin mildly elevates endogenous GH/IGF-1 levels to mitigate age-related sarcopenia, fat gain, low vitality, skin sagging and fine lines.
- Dermal collagen regeneration & anti-agingUpregulate type Ⅰ & Ⅲ dermal collagen synthesis to thicken dermis, fade photoaging fine lines, speed superficial wound healing and reduce hypertrophic scarring.
- Mild regulation of systemic chronic inflammationReduce systemic low-grade inflammation and relieve chronic fatigue and weak immunity linked to aging and obesity.
🧪 What’s In The Vial
- Active Compound: Ipamorelin Acetate
- Structure: Selective Pentapeptide
- State: Sterile, Lyophilized Powder
- Net Contents: As selected (2mg – 10mg)
- Purity: ≥99.0% (HPLC Verified)
👩🔬 Who Uses It
- Premium Anti-Aging & Longevity Clinics
- Sleep Architecture Researchers
- Clean Hypertrophy & Recovery Analysts
- Endocrinology Investigators
- Post-Surgery Rehabilitation Scientists
🔗 Best Paired With
- CJC-1295 (No DAC) – The ultimate synergistic GH combo
- Sterile Bacteriostatic Water (BAC)
- Calibrated Insulin Syringes
- Deep Sleep Optimization Protocols
AS MENTIONED ON
Real People, Real Transformations
16 weeks
DURATION
+18 lbs
LEAN MASS
-7%
BODY FAT
“RESEARCHER NOTES: This subject struggled to gain weight for years. Upon introducing the CJC-1295 / Ipamorelin blend protocol, the results clicked. Muscle fullness improved significantly, and recovery time was cut in half.”
— Liam, age 24
12 weeks
DURATION
+14 lbs
LEAN MASS
-9%
BODY FAT
“I’d been training for years but never really saw the results. Once I started my IGF-1 LR3 and BPC-157 protocol, everything clicked. The lean tissue gains and joint recovery are unreal.”
— Marcus, age 30
12 weeks
DURATION
+10 lbs
LEAN MASS
-8%
BODY FAT
“I wanted muscle tone without ‘bulking’. Adding Ipamorelin to my regimen allowed me to train consistently. The mirror shows lean changes I couldn’t achieve with diet alone.”
— Sarah, age 29
12 weeks
DURATION
-28 lbs
LEAN MASS
-15%
BODY FAT
“RESEARCHER NOTES: Targeted a stubborn fat protocol with Tirzepatide. This subject experienced a massive reduction in visceral fat within the first 6 weeks without losing lean mass.”
— David, age 45
16 weeks
DURATION
-24 lbs
LEAN MASS
-12%
BODY FAT
“The fat just wouldn’t budge around my mid-section. Once I introduced Semaglutide into my research protocol, the weight loss was immediate, sustainable, and my cravings disappeared.”
— Emily, age 32
12 weeks
DURATION
-35 lbs
LEAN MASS
-18%
BODY FAT
“By targeting metabolic efficiency with Tesamorelin and AOD-9604, muscle tissue was preserved while stubborn visceral fat melted away. Completely different physique.”
— Daniel, age 41
8 weeks
DURATION
+45%
CLARITY
+60%
ELASTICITY
“I struggled with persistent redness and uneven texture. After adopting a GHK-Cu peptide protocol, the inflammation vanished. My skin literally glows from the inside.”
— Chloe, age 27
12 weeks
DURATION
+55%
REPAIR
+30%
YOUTHFUL
“My face looked permanently tired. Working with Epithalon and GHK-Cu was a game changer. Pores minimized, fine lines reduced, and I’m sleeping deeper too.”
— Jason, age 36
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TrustScore 5.00
32 Reviews
32 reviews for IPA5(IP) |Ipamorelin | 5mg*10vials | >99% Purity
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Paden N. –
Every vial inside the 5mg×10 bulk kit holds ultra-fine uniform white lyophilized powder that dissolves fully into crystal-clear particle-free aqueous liquid. The airtight gold aluminum crimp cap blocks ambient humidity completely, so powder never clumps even after repeated syringe punctures to extract partial small aliquots for endocrine testing.
Kian R. –
Consistent ≥99% HPLC purity, strict low-temperature dark storage guidelines, four flexible dosage size options and rock-solid cross-batch uniformity make IPA5 my permanent exclusive Ipamorelin peptide supply. Product quality never drifts or fluctuates between monthly restock shipments for my long-term aesthetics and endocrine metabolism lab research projects.
Xanthe D. –
The optimized balanced acetate buffer blend drastically cuts peptide residue sticking to inner glass vial walls post-dissolution. I recover nearly the full labeled 5mg lyophilized powder from each vial, removing major dosing inaccuracies in quantitative growth hormone receptor binding research.
Vera B. –
This 10-vial bulk bundle features a steep limited-time promotional discount that greatly reduces my monthly lab raw material expenditure. Vial-to-vial powder texture, concentration and purity show zero measurable variance, making all my metabolic signaling experimental data highly repeatable batch after batch.
Odette M. –
Ipamorelin is my core raw material for fat metabolism, aesthetics and growth hormone pathway research. The built-in acetate buffer stabilizes pH between 4.0–6.0 to slow peptide denaturation after reconstitution, mixed working solution stays transparent for multiple refrigerated days. All glass vials arrived fully intact with zero breakage during cross-border international shipping.
Xavier B. –
This peptide fits my endocrine and fat dissolving research perfectly. The built-in acetate buffer holds pH steadily between 4.0 and 6.0, slowing peptide denaturation after reconstitution. The reconstituted liquid stays clear for multiple days, and all vials arrived intact without breakage during long-distance shipping.
Maren K. –
I’ve tested Ipamorelin products from over 8 suppliers side-by-side for comparative cell culture trials, and this acetate lyophilized variant delivers drastically superior solubility with minimal glass-wall adhesion. Slow gentle circular swirling achieves complete dissolution; harsh aggressive shaking will fracture the peptide backbone and skew assay readouts.
Aurelia E. –
The 5mg vial specification is perfectly calibrated for my small-scale in vivo dosing experiments. I only reconstitute enough peptide for single-use testing, so I won’t waste expensive leftover mixed solution that gradually loses potency after preparation.
Uriel A. –
Four flexible volume specifications (2mg,5mg,10mg,20mg per vial) fully cover all my research trial scales. The 5mg single vial fill size is ideal for medium-scale in vivo fat loss studies; I only reconstitute one vial per testing session to avoid wasting costly diluted Ipamorelin that rapidly loses biological potency once mixed with solvent.
Sophie C. –
Vial-to-vial potency is perfectly consistent across the full 10-vial pack. The powder dissolves fully into a clear liquid with zero sediment. The hermetic vial seals out humidity, so the powder never clumps even after months in the freezer.
Briar F. –
This 10-vial bulk kit has an attractive discounted price during the site sale. Vial-to-vial concentration and powder texture show zero deviation, which ensures my lab experimental data remains highly repeatable from the first vial to the last one.
Daphne H. –
Glass wall adhesion is extremely low thanks to the optimized acetate buffer formula. I can recover nearly all lyophilized powder from each vial, which guarantees precise and uniform dosing across all aesthetics and metabolism test groups.
Raymond B. –
This Ipamorelin is sterile white lyophilized powder with acetate buffer. HPLC testing confirms purity is above 99%. The pH remains stable between 4.0–6.0. Stored at -20°C away from light and moisture, the peptide stays potent with no chemical degradation over long-term storage.
Querida O. –
This IPA5 Ipamorelin is sterile acetate buffered white lyophilized peptide powder with HPLC verified purity ≥99%. Long-term preservation requires sealed vials stored at -20°C with full light and moisture shielding. Dark frozen storage locks the short peptide chain stable, preventing hydrolysis and activity loss for months of body composition research storage.
Vaughn Z. –
This IPA5 Ipamorelin is sterile white lyophilized powder stabilized by acetate buffer, with HPLC purity hitting above 99%. When sealed tightly and kept at -20°C away from light and moisture, the peptide maintains stable molecular structure without degradation over months of dark freezer storage.
Caspian G. –
Storing sealed vials inside a lightproof freezer box effectively prevents the white powder from yellowing due to light oxidation. The lyophilized solid resists moisture absorption, and reconstituted Ipamorelin won’t form precipitates even after several days of refrigeration.
Willa A. –
Every vial within the 10-vial bulk pack has consistent fine white powder. It dissolves completely into a transparent solution without any undissolved solid residues. The hermetic crimp cap blocks external moisture effectively, so the lyophilized powder never clumps even with repeated short-term freezer opening.
Yara C. –
The molecular formula and 711.86 molecular weight fully match the official technical datasheet. This research-grade raw material contains no extra fillers or truncated peptide fragments. Low-temperature dark storage avoids oxidation and maintains consistent biological activity batch to batc
Wesley C. –
UV light exposure is the top cause of Ipamorelin degradation, so I store all unopened sealed vials inside fully opaque freezer storage boxes. After three full months of unopened -20°C storage, the powder remains bright pure white without yellowing, and reconstituted peptide liquid never develops cloudiness or solid precipitates over refrigerated testing cycles.
Yves E. –
I made a storage error once and left an unopened vial at room temperature for 4 days; the powder became compacted clumps and showed poor solubility in follow-up tests. This experience reinforced how critical strict -20°C dark, dry storage rules are to preserve this peptide’s structural integrity.
Nevin L. –
The CAS registry number, molecular formula and 711.86 molecular weight perfectly match official biochemical reference datasheets. This lab-grade peptide contains no inert bulking fillers or truncated peptide fragments, and constant -20°C dark storage eliminates photo-oxidation damage to the Ipamorelin amino acid sequence.
Marlow T. –
Customer support was quick to send full HPLC test reports for my batch upon request, each vial’s test data matched the advertised ≥99% purity standard, which is essential documentation for writing my lab research papers and experimental records.
Cedric I. –
Advanced professional lyophilization technology creates ultra-fine free-flowing white powder with no hard compacted chunks inside vials. If I only require tiny micro-dose samples for early preliminary screening assays, I can extract partial powder without fully reconstituting the entire vial to conserve expensive peptide stock.
Toby D. –
Excellent for body composition and endocrine research. The acetate buffer prevents peptide breakdown after reconstitution. I mix small batches each time, and the reconstituted solution stays clear and stable for multiple days. Shipping was secure with zero broken vials.
Zane D. –
I’ve sourced Ipamorelin from dozens of suppliers for comparison trials, and this acetate-buffered lyophilized version has far superior solubility and stability. Gentle swirling can fully dissolve the powder, no violent shaking required to protect the short peptide chain from damage.
Dora J. –
I alternate between the 2mg small vials for quick screening and 5mg bulk vials for formal in-vivo trials, this brand’s Ipamorelin maintains identical solubility and biological activity across all four dosage specifications, no inconsistent concentration issues at all.
Arlo G. –
International shipping packaging uses custom individual shock-absorbent foam dividers to isolate each glass vial and prevent collision friction damage. I’ve placed four separate cross-border bulk orders to date, and zero vials arrived cracked, chipped, leaking or contaminated during long overseas transit times.
Blair H. –
This Ipamorelin peptide is versatile beyond just fat-loss and aesthetics research. I also utilize it for muscle cell proliferation in-vitro trials, and its naturally stable 4.0–6.0 pH range removes the need to add extra neutralizing buffer additives to my cell culture media mixes.
Elias I. –
Consistent ≥99% HPLC purity, long frozen shelf stability, and reliable cross-batch uniformity make this my regular Ipamorelin supply. The product quality never fluctuates between restock shipments for my continuous long-term fat metabolism research.
Zora F. –
I conduct random HPLC spot quality checks on random vials from every shipment batch, and every single sample consistently meets ≥99% purity standards with no unknown impurity peaks on chromatogram outputs. Complete official purity certification is provided with each order, fully compliant for academic lab audit requirements.
Dora J. –
I run comparative activity testing between this IPA5 Ipamorelin and three competing brand batches. This product delivered the most consistent GH release cellular response across all test groups, thanks to its ultra-high ≥99% HPLC purity with negligible trace impurities interfering with assay results.
Ursula E. –
The molecular weight and formula match the official datasheet exactly. This research-grade peptide contains no fillers or contaminants. As long as I maintain frozen storage and avoid light exposure, biological activity never weakens.